Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome

Submitted: 8 August 2011
Accepted: 11 May 2012
Published: 7 June 2012
Abstract Views: 1606
PDF: 510
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The aim of this study was to evaluate the efficacy of omalizumab in the treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), evaluated by visual analogue score for pain and urgency- frequency, O’Leary-Sant IC symptom and problem index questionnaire, Pain Urgency Frequency questionnaire and Patient Global Assessment questionnaire. Four female patients with a diagnosis of IC/BPS were included in the study, with an age between 20 and 39 years. In the first patient the subjective final evaluation was of a marked improvement. The second patient had a moderate improvement of the subjective final evaluation. The third patient considered her overall clinical situation to have slightly improved after treatment. One 32-year-old patient, with multiple allergies, discontinued treatment after 3 months and could not complete the study due to side effects. Omalizumab was subcutaneously administered to patients with IC/PBS; it induced both a subjective and objective improvement of symptoms in 2 patients enrolled in the study.

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Novartis

How to Cite

Porru, D., Bucchioni, E., Macchi, M., Leva, F., Parmigiani, A., Barletta, D., … Rovereto, B. (2012). Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome. Urogynaecologia, 26(1), e8. https://doi.org/10.4081/uij.2012.e8

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